The goal of the registry is to collect de-identified (anonymous) information on patients diagnosed with primary sclerosing cholangitis (PSC) in order to increase and accelerate research, enable clinical and drug trials, and find effective treatments for PSC. PSC is a poorly understood disease for which there are currently no effective therapies and no known cure. We hope that our patient registry will provide a forum for PSC patients from all over the world to share their medical information and provide researchers with data that will lead to a better understanding of PSC.